Spravato® Treatment for TRD

Adding Spravato® for Treatment Resistant Depression is Proven to Reduce Symptoms.

If you’ve taken two or more oral antidepressants and you’re still experiencing the symptoms of depression, it’s likely that you have treatment-resistant depression (TRD). Spravato® is the only nasal spray treatment indicated for people who have taken two or more oral antidepressants and still experience depressive symptoms. Camden Interventional Psychiatry is a certified treatment center for Spravato® therapy.

Decided to try Spravato®?

Once you and your healthcare provider have decided that Spravato® is your best next option, you can start planning for your first treatment. Schedule an initial appointment at Camden Interventional Psychiatry, where the team will explain the process, benefits, and possible side effects. Spravato® is covered by most major health insurance providers, so you’ll be responsible for your normal co-pay amount.

What to expect: Planning for your first treatment

  • You will administer Spravato® nasal spray yourself, under the supervision of the Camden Interventional Psychiatry team.

  • After you’ve taken the initial treatment, you’ll be observed for two hours. We will monitor you for possible side effects during this time, and you will be relaxing in comfortable environment.

  • Because of the possible side effects affecting coordination, you won’t be able to drive or operate heavy machinery until the next day. You will need to plan for rides on your treatment days.

  • Spravato® is taken in combination with an oral antidepressant.

  • You’ll take Spravato® once a week for the first four weeks. Our office will work with you to schedule these appointments.

  • After the first four weeks, you and your doctor will determine if treatment should be continued. If you’re benefitting from Spravato® treatments, your dosage and frequency will be determined.

Spravato® treatment allows the participant to experience relief from depressive symptoms that have been resistant to multiple oral antidepressants.

Call our office to schedule your initial meeting. (207) 218-5067

What happens at your first visit to our Spravato® treatment center?

The first visit consists of a consultation, where we will cover the following:

  • Camden Interventional Psychiatry will ensure that we’ve received all necessary medical information from healthcare provider.

  • We will conduct our own assessment to determine if Spravato® treatment is right for you.

  • We’ll verify your insurance information to make sure that you’re eligible for treatments.

  • If we move forward with Spravato® treatment, we will build a plan with you, enrolling you in the Spravato® Risk Evaluation and Mitigation Strategy (REMS) program.

  • Your regular healthcare provider will continue to be involved with your care during your Spravato® treatments, and will answer questions or address concerns as you undergo treatment. Remember to follow up with your healthcare provider after your treatment plan is created if you have any questions.

What to know about ongoing treatment center visits:

  • You may start treatment as soon as your second visit.

  • Be sure to bring a form of entertainment, like your favorite playlist and headphones, or a book. Remember, you’ll be monitored for two hours after your initial treatment.

  • Make sure that you have transportation arranged to get home, as you won’t be able to drive or operate heavy machinery until the next day.

  • Avoid eating for two hours before, and drinking liquids 30 minutes before the treatment session. Some patients may experience nausea or vomiting.

  • If you take a nasal corticosteroid or nasal decongestant medicine, take these medicines at least one hour before taking Spravato®.

FAQs

Can Spravato® benefit depressive symptoms of MDD with suicidal thoughts or actions?

SPRAVATO® is proven effective for depressive symptoms in adults with major depressive disorder (MDD) with suicidal thoughts or actions (MDSI).

In clinical studies of adults with MDD with suicidal thoughts or actions, those who took SPRAVATO® and an oral antidepressant experienced a greater reduction of depressive symptoms at 24 hours compared to those who received a placebo plus an oral antidepressant.*

*Based on an overall score on a standardized rating scale.

What are the possible side effects of Spravato®?

SPRAVATO® can cause serious side effects, including:

  • Sedation and dissociation. SPRAVATO® may cause sleepiness (sedation), fainting, dizziness, spinning sensation, anxiety, or feeling disconnected from yourself, your thoughts, feelings, space and time (dissociation).

  • Tell your healthcare provider right away if you feel like you cannot stay awake or if you feel like you are going to pass out.

  • Your healthcare provider must monitor you for serious side effects for at least 2 hours after taking SPRAVATO®. Your healthcare provider will decide when you are ready to leave the healthcare setting.

  • Respiratory depression was observed with the use of SPRAVATO®; additionally, there were rare reports of respiratory arrest.

    Your healthcare provider must monitor you for serious side effects for at least 2 hours (including pulse oximetry) after takingSPRAVATO®. Your healthcare provider will decide when you are ready to leave the healthcare setting.

  • Abuse and misuse. There is a risk for abuse and physical and psychological dependence with SPRAVATO® treatment. Your healthcare provider should check you for signs of abuse and dependence before and during treatment with SPRAVATO®.

    Tell your healthcare provider if you have ever abused or been dependent on alcohol, prescription medicines, or street drugs.

    Your healthcare provider can tell you more about the differences between physical and psychological dependence and drug addiction.

  • SPRAVATO® Risk Evaluation and Mitigation Strategy (REMS).

    Because of the risks for sedation, dissociation, respiratory depression, and abuse and misuse, SPRAVATO® is only available through a restricted program called the SPRAVATO® Risk Evaluation and Mitigation Strategy (REMS) Program. SPRAVATO® can only be administered at healthcare settings certified in the SPRAVATO® REMS Program. Patients treated in outpatient healthcare settings (e.g., medical offices and clinics) must be enrolled in the program.

How long until I’m back to normal?

If any of the common side effects do occur, they usually happen right after taking Spravato® and go away the same day.